The Lancet
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Michael Connolly 
Sarah Weller 
West Africa on alert for haemorrhagic fevers—Cases of #Ebola virus disease and Marburg virus disease have prompted national and regional emergency responses. @pauladepoju for World Report. hubs.li/H0VHdNJ0
NEW Research—Heterologous ChAdOx1 nCov-19–BNT162b2 immunisation w/ 10–12-week interval is well tolerated & improves immunogenicity vs homologous ChAdOx1 nCov-19 vax w/ 10–12-week interval & BNT162b2 vax w/ 3-week interval
Study from Prof Sander & co bit.ly/3ADQHvh
Retweeted by The Lancet Explore more interesting, educational images of medical problems, clinical signs, or investigations using #TLClinicalPic.
#COVID19 followed by #mucormycosis carries a very high mortality rate and timely detection, antifungal therapy, and aggressive surgical debridement remain key factors in the management.
New Clinical Picture—#Mucormycosis after #COVID19 in a patient with diabetes.
Watch author, Samendra Karkhur, explain the case of a 44-year-old man in the video below. thelancet.com/journals/lance…
"Ultimately, our work is about reducing the impact of extreme heat—to improve health and quality of life for all."
Meet co-lead author of new #LancetHeatAndHealth Series, @ollie_jay13 @Sydney_Uni. hubs.li/H0VHdRn0
We need to find ways to cool those most vulnerable to heat now more than ever ☀️
@Sydney_Uni Prof @ollie_jay13 & Prof @kristie_ebi's new #LancetHeatAndHealth series calls for evidence-based planning & offers sustainable cooling strategies to help combat our #ClimateCrisis.
Retweeted by The Lancet 
What's cooking? A new approach to mental health research.
The @wellcometrust Active ingredients for addressing youth anxiety and depression Series is FREE w/email registration.
thelancet.com/series/active-…
Retweeted by The Lancet 
🆕 On this week's cover, a quote from the#LancetHeatAndHealthh Series.
Also in issue: Correspondence on face#maskss, physical distancing, and eye
protection, climate disasters and global social medicine, gendered#ageismm, and more:hubs.li/H0VHdzq0YV
A pair of new studies find a "very concerning" rise in the number of climate-related deaths and paint a picture of a world where people struggle with regular temperature extremes cnn.it/3z4J54P
Retweeted by The Lancet "There is a danger that promises and pledges to tackle the #ClimateCrisis will not be reflected in decisive action and effective policies."
Read the #LancetHeatAndHealth linked Editorial: Health in a world of extreme heat hubs.li/H0VHgLR0
The current trajectory of #ClimateChange means measures to protect health and life against extreme heat will be as important as mitigation efforts.
Tailored approaches in settings where people may be vulnerable to extreme heat—such as care homes, slums, schools—are essential
🏙️ Urban & landscape interventions that will help protect people from the effects of extreme heat include:
-Building adaptations
-Reducing carbon emissions in cities
-Heat action plans—with early warning systems and robust surveillance & monitoringhubs.li/H0VHgvR0HL
Air conditioning, although effective at cooling, is unsustainable and unaffordable for some. Cooling strategies are needed at building and urban & landscape levels—but individuals can do many things to cool themselves down too 👇G
When exposed to extreme heat stress, the body’s ability to regulate its internal temperature can be overwhelmed, leading to heat stroke, cardiorespiratory events, and other health problems
Learn more about the health effects of extreme heat hubs.li/H0VHgqm0
>356,000 deaths were related to heat in 2019, suggests new #GBDStudy using data from 9 countries
Cold temperatures are currently linked with more deaths (1.3 million)—but ⬆️ global temperatures mean extreme heat poses an increasing threat to health hubs.li/H0VHHc80
🆕 To avert preventable deaths in an ever-hotter world, sustainable changes in behaviour and to the built environment are urgently needed alongside continued efforts to tackle#ClimateChangee
Read the new#LancetHeatAndHealthh Serieshubs.li/H0VHgNm0bl
"Our task is to identify pathways that improve access to technology & innovations that support better & more equitable cancer control...while strengthening health systems"
Co-chairs @FeliciaKnaul @marykge @Pattyjannet1 detail why the time is right for this new Commission
#Cancer cases are expected to increase from 19.3 to 28.4 million by 2040. To meet this rising burden, innovative solutions that promote synergy across health systems will be crucial
Announcing a new @TheLancet Commission on cancer and health systems thelancet.com/journals/lance…
A Rapid Review published in our September issue discusses the post-viral effects of COVID-19 in the olfactory system and their implications thelancet.com/journals/laneu…
Retweeted by The Lancet Our Editorial this month discusses the lack of progress that has been made towards WHO's global targets for reducing the burden of dementia thelancet.com/journals/laneu…
Retweeted by The Lancet Our September issue is available online now, with content on COVID-19, multiple sclerosis, acute ischaemic stroke, Alzheimer's disease and frontotemporal lobar degeneration, and myelin-oligodendrocyte glycoprotein antibody-associated disease thelancet.com/journals/laneu…
Retweeted by The Lancet The above link for this Comment is incorrect. Please use this one: hubs.li/H0VDcyl0.
We are absolutely thrilled to introduce our new Youth Advisory Panel within our International Advisory Board
Youth participation is key to effecting change & we're looking forward to the valuable perspectives they'll bring to our work. Here they are 🧵👇bit.ly/3g8TmFviMq
Retweeted by The Lancet Our September issue is here!
With articles on global #breastfeeding practices, neurological complications of #COVID19, fixed-dose bictegravir for #HIV, familial hypercholesterolaemia #FH, & much more
Cover art by Bella Nagashima, age 7
bit.ly/3zkpFIW
Retweeted by The Lancet Although GBD data have been an important policy and advocacy lever, country-led and country-focused approaches will be key to will illuminating under-5 mortality disparities.
Read the linked Comment from @CherylMoyer10 and @waiswap. hubs.li/H0VCzLw0
What is needed to improve global U5MR & NMR?
1⃣ Quality perinatal & newborn care
2⃣ Essential interventions—vaccines & infection prevention
3⃣ Focus on equity, poverty reduction, & education
4⃣ Investment in research & strengthening health systems
65 (32%) of the 204 countries and territories assessed are not on track to meet either SDG 3.2 target by 2030—mostly in sub-Saharan Africa and south Asia.
Within-country disparities must be examined alongside action on other determinants of health.
The study found under-5 mortality (U5MR) decreased from 71 deaths per 1000 livebirths in 2000 to 37 in 2019.
Correspondingly, for neonates (NMR): 28 deaths per 1000 live births in 2000 to 18 in 2019.
Global child mortality declined by almost half from 2000-2019—but progress remains slower in neonates.
New @IHME_UW #GBDStudy reports levels and trends in neonatal and under-5 mortality (#SDG 3.2) from 2000-2019 and scenarios for 2030: hubs.li/H0VCnZF0
Key findings ⬇️
This year's #WorldHumanitarianDay calls for greater action on the #ClimateEmergency and its immediate consequences for the climate-vulnerable.
Their needs must top the agenda at @COP26 in November. Read more 👇#TheHumanRaceebit.ly/2W7lIswt
The compassionate acts of #humanitarian workers "should be celebrated as those things which sustain communities...and keep spirits alive."
@rachelcogs on recognising the importance of palliative care in humanitarian response: hubs.li/H0VC08x0 #WorldHumanitarianDay
#Humanitarian workers often find themselves at the crossroads of conflict, social and economic fragility, a global #pandemic, and a growing #ClimateCrisis.
They need more than honour, writes @EtienneVincentL & colleagues—they need life-saving protection. hubs.ly/H0VBZKZ0
It's @UN #WorldHumanitarianDay, an opportunity to advocate for the well-being and dignity of people affected by crises, and to protect the #humanitarian workers who support the world's most vulnerable.
Small Island Developing States (SIDS) face unique challenges that impact health—but gaining global attention can be difficult with such small populations.
In June, the first SIDS Summit for Health was held. @Jacquithornton reports: hubs.li/H0Vy0B-0
"I like breaking new ground, and pushing to the next frontier."
Discover the life and work of @BrooksLaSureCMS, innovative US federal health director and the first Black woman to lead @CMSGov. Read the Profile by @susanjaffe. hubs.li/H0VwtmC0
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🎧 A feminist recovery from#COVID199—what it looks like and how feminism can inform the policies needed to rebuild.
@sarah_kaplann, Director of@GenderEconomyy, joins@TheLancett's@jocalynclarkk &@JessamyBagenall in a new#LancetVoicee:hubs.li/H0Vw3Tl0Y
#GenerationEqualityy9
"The statistical analysis in this small study does not account for potential confounding factors. However, the robust inhibition of #variants including the #DeltaVariant further supports heterologous ChAdOx1-S/BNT162b2 vaccination."
Authors advise further and larger studies.
New research letter reports small study analysing plasma from ChAdOx1-S-primed vaccinees after homologous (same) ChAdOx1-S or heterologous (mixed) BNT162b2 boost to compare neutralising activity against #variants of concern, including the #DeltaVariant. hubs.li/H0VvBLR0
The September Issue of @TheLancetEndo is now online, featuring #gender disparities, type 1 #diabetes, #cardiovascular disease, #genetics, #COVID19, #obesity, type 2 diabetes, #nutrition, #bone health, #childhoodcancer, #neuroendocrinology & more bit.ly/3yXm2sA
Retweeted by The Lancet "Every country and every community must be able to rapidly detect, report, and respond effectively to any potential major new health threat."
Thomas Frieden and colleagues propose a 7-1-7 framework to make the world safer from future #pandemics: hubs.li/H0VrnFv0
"...she saw infants with early-onset #scoliosis as "drooping flowers" who with the right care could be helped to grow straight without radical surgery..."
Discover surgeon Min Mehta, who developed Mehta casting for early-onset #scoliosis. #WomenInScience hubs.li/H0Vp-cZ0
"The social is all too often overlooked in health-care systems..."
@MedAnthDoc and colleagues discuss the concept, histories, and practices of global social medicine—underscoring the significance of the social dimensions of sickness, medicine, and health. hubs.li/H0VpKC_0
📢@LancetGHH is still welcoming submissions on the theme 'What is wrong with global health?'
Read the first responses in the thread below and submit your work by the end of September:bit.ly/3iPHXN1ntwitter.com/TheLancet/stat…d
"The consequences of the #COVID19 pandemic have worsened an already unacceptable global burden of disease for respiratory cancers, as well as highlighting substantial global health inequities, which continue to grow and must be addressed."
NEW Editorial: bit.ly/2XAsNTl
Retweeted by The Lancet NEW Research—Age-standardised incidence and death rates due to tracheal, bronchus, lung cancer and larynx cancer 📈 in some pop—namely, in lower SDI quintiles and among women
GBD study of respiratory tract cancers and associated risk factors, 1990–2019bit.ly/2W0bWZg7O
Retweeted by The Lancet NEW—Benefits of #COVID19 vaccines far outweigh very rare risk of Bell's palsy, confirms first large-scale population-based study on the association between the adverse event and #CoronaVac or #Pfizer-BioNTech vaccination. Read in @TheLancetInfDis: hubs.li/H0VnhnZ0
Once you've answered, find out if you were correct and access the full Clinical Picture case study here: hubs.li/H0VlvPy0
#TLClinicalPic
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