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A low dose of the Moderna #COVID19 vaccine generated long-lived T cell immunity that was equivalent between younger and older patients, and which could be enhanced by the presence of cross-reactive T cells, researchers report in Science. fcld.ly/usdfrq3
New research in Science reports a novel strategy for boosting the performance of Shewanella microbial fuel cells, which achieves a "record-setting microbial fuel cell power density." Learn more ⬇ fcld.ly/59z1rc5 #SciencePerspective: fcld.ly/jgoxglh
"This year’s United Nations Climate Change Conference...must be a turning point—the moment when the world heeds scientific findings and collectively rises to meet the greatest challenge of our time." A new #ScienceEditorial by @JaneLubchenco & @JohnKerry: fcld.ly/6b4zn3x
New this week in Science: When #CRISPR and Caspase meet, a look at social evolution in mammals, and titanium gets some twins. 📕:fcld.ly/j6zd5w5tu
At the Wellcome Collection, a pair of exhibitions challenge visitors to embrace a more encompassing view of contentment, "offer[ing] an unconventional perspective on the types of things that make us feel good," argues a new @SciMagBooks review. fcld.ly/7ghgdpj
Tumor draining lymph nodes are more than a passive route exploited by tumors; rather, they actively remodel in response to tumor growth to directly contribute to immunosuppression and metastasis, argues a new @SciImmunology Review. fcld.ly/vhyps2n
The NIH has announced a nearly $470 million grant to enroll up to 40,000 people infected with #SARSCoV2 in a study that will probe the causes of Long COVID. fcld.ly/z1pv952
Retweeted by Science Magazine
NASA's new moonshot: Beginning next year, an armada of low-cost robotic landers sponsored by NASA will begin to arrive on the Moon. Learn more ➡ fcld.ly/jipv1fn #LongReads @ScienceVisuals
Over time, ~20% of chronic cocaine users lose control & become addicted. A new study discovered a synaptic mechanism in mice that underlies the modulatory role of brain serotonin in reducing the likelihood of transition to compulsion & eventually addiction fcld.ly/75xm6nm
Scientists have provided new insights into how intense thunderstorms drive the injection of water vapor from the troposphere to the stratosphere. Their #ScienceResearch proposes a feature called a “hydraulic jump,” as part of this process. fcld.ly/gfc8nr5
"I had become a ghost author, my contributions used without credit." This week's #ScienceWorkingLife: fcld.ly/7a29hr0
A new study in mice in @scisignal links tolerance and pain sensitivity from morphine to a mechanism in glial cells, suggesting that suppressing this pathway could counteract these two major drawbacks of long-term opioid use. fcld.ly/htmodxi
On 31 August 2021, we gave our website a top-to-bottom redesign. In a new post to the Editor's Blog, @hholdenthorp reflects on the history of the Science journal going online. fcld.ly/itoikr8 How it started: How it’s going:
New software helps off-the-shelf #drones fly faster, by flying smarter. Programmed on the path optimization algorithm, a drone completed a complex course faster than #robots controlled by professional drone pilots. Read more in @SciRobotics: fcld.ly/lauzhmx
In a new study, grad students reported that research activities, which were relatively unstructured and provided little opportunity for positive feedback, tended to worsen their symptoms of depression—while teaching, on the other hand, helped them cope. fcld.ly/k2wfr1u
Retweeted by Science Magazine
As performance reviews become more common, here’s how you can get the most out of them. fcld.ly/7075k6v #AcademicTwitter @ScienceCareers
A novel technique for #SARSCoV2 antibody detection and more in this week’s Science Advances: fcld.ly/cyisz7i
Retweeted by Science Magazine
An analysis of patient samples collected before the #COVID19 pandemic shows that killer #Tcells that can recognize #SARSCoV2, despite never having encountered the virus before, are located in tissues, rather than circulating in blood. In @SciImmunology: fcld.ly/3diemi1
After mild traumatic brain injury, a molecule called complement factor C1q may play a role in the secondary effects of brain injury, such as sleep disruption, epileptic activity, and inflammation, according to a new Science study in mice. fcld.ly/z6j4hdi
Only 1.5% to 7% of the modern human genome is uniquely human, according to a recent @ScienceAdvances analysis of Neanderthal, Denisovan, and human genomes. fcld.ly/o48ls44
The use of contact tracing apps has shown promise in helping reduce the spread of transmissible diseases. However, a new #SciencePolicyForum shows how their use is not equal: “We must...build tools...so that their use enables greater health care equity.” fcld.ly/cmykiga
A recently approved mining project named Dominga threatens the endemic species and fragile ecosystems of northern Chile, argues a new #LetterToScience: "Given the high environmental costs of Dominga, the project should be halted." fcld.ly/6f6mglm
Researchers seeking to understand the origins of #CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed “OMEGA,” that could be harnessed for genome editing in human cells. fcld.ly/m54x8a9 #ScienceResearch
A new study from @ScienceAdvances finds tropical forests are becoming fragmented at an alarming rate, which could lead to an additional 500 million metric tons of carbon emitted per year. fcld.ly/5f0fyks
Mitochondrial disease: Replace or edit? A new #SciencePerspective evaluates the potential therapeutic use of mitochondrial replacement therapy and mitochondrial DNA editing in the treatment of #mtDNA diseases. fcld.ly/ysnyahb
Pre-existing antibodies to coronaviruses correlated with less severe disease and better outcomes following #SARSCoV2 infection, reports a longitudinal study in patients with mild, severe, or fatal #COVID19. New in @SciImmunology: fcld.ly/lyy80x4 @ragoninstitute, @MIT
Making ribosomes in human cells: New research in Science provides novel insights into human ribosome assembly by using cryo–electron microscopy, x-ray crystallography, and functional studies. Learn more ⬇ fcld.ly/z45hc5e
You probably don’t expect much sports coverage in a publication named Science. So, it might have come as a surprise to see the athletic feat of a fox squirrel on our 6 August cover. Here's a look at how those fleeting leaps were captured: fcld.ly/rt7qd1b @ScienceVisuals
New bispecific antibodies target multiple regions of the #SARSCoV2 spike protein, enabling them to strongly neutralize variants of concern—including #Delta—in animal models. New in @ScienceTM: fcld.ly/ueu7e6j @NIAIDNews
A new #ScienceReview presents a science-driven framework—“the MPA guide”—to aid the design and evaluation of Marine Protected Areas, which could help improve the design, implementation and evaluation of existing and future MPAs. fcld.ly/b0s25rt
New findings in @ScienceAdvances show the mysterious zona incerta brain region both triggers and suppresses anxious behaviors in mice, offering insights that could be used to help treat anxiety in patients with #Parkinsons disease. fcld.ly/wkdxvft
A low dose of the Moderna #COVID19 vaccine generated long-lived T cell immunity that was equivalent between younger and older patients, and which could be enhanced by the presence of cross-reactive T cells, researchers report in Science. fcld.ly/usdfrq3
Elevated levels of serotonin can prevent the development of compulsive cocaine seeking and addiction in mice, researchers report in Science. The findings help to resolve the biological markers of addiction risk. fcld.ly/mhc9cm8 #ScienceResearch
A genomic analysis of #SARSCoV2 in Africa reveals the first phase of the pandemic was caused by importations from outside Africa, while the second, more deadly phase was fueled by intracontinental transmission and led to emergence of variants of concern. fcld.ly/7yti1ay
A human monoclonal antibody targeting the conserved spike stem helix in β-coronaviruses reduces #SARSCoV2 burden in hamsters, researchers report in Science. The results could inform development of pan-β-coronavirus vaccines eliciting broad protection. fcld.ly/kado5mu
An analysis of 14 populations encompassing 11 language families in northeast Asia finds a correlation between the grammatical structure of a population’s language and its genetic history. fcld.ly/e2d3h1r @ScienceAdvances
The hunt for #SARSCoV2’s ancestors heats up: Researchers have found a host of coronaviruses similar to SARS-CoV-2 in bats and pangolins in China and neighboring countries. Learn more from a recent @NewfromScience Feature: fcld.ly/5xr7bht @ScienceVisuals
Over time, ~20% of chronic cocaine users lose control & become addicted. A new study discovered a synaptic mechanism in mice that underlies the modulatory role of brain serotonin in reducing the likelihood of transition to compulsion & eventually addiction fcld.ly/75xm6nm
Scientists have provided new insights into how intense thunderstorms drive the injection of water vapor from the troposphere to the stratosphere. Their #ScienceResearch proposes a feature called a “hydraulic jump,” as part of this process. fcld.ly/gfc8nr5
It's not too late! Join #ScienceWebinars on Wednesday 9/15 at 12p for: Imagining the future of #neuromodulation: New applications to treat disease and enhance health. Hear from the panel, including the 2021 Science-PINS Prize for Neuromodulation winner. fcld.ly/ikwqhaq
"I had become a ghost author, my contributions used without credit." This week's #ScienceWorkingLife: fcld.ly/7a29hr0
A new study in mice in @scisignal links tolerance and pain sensitivity from morphine to a mechanism in glial cells, suggesting that suppressing this pathway could counteract these two major drawbacks of long-term opioid use. fcld.ly/htmodxi
On 31 August 2021, we gave our website a top-to-bottom redesign. In a new post to the Editor's Blog, @hholdenthorp reflects on the history of the Science journal going online. fcld.ly/itoikr8 How it started: How it’s going:
AgnathaX, a lamprey-inspired #robot, successfully slithered like an eel by aligning its central and peripheral control systems, simulating a process known in #biology as entrainment. Learn more in @SciRobotics: fcld.ly/rqojllu
New research in Science introduces MIC-Drop, a new #CRISPR screening platform for performing large-scale reverse-genetic screens in zebrafish. The approach can be adapted for use in diverse model organisms. fcld.ly/6lkak93 #ScienceResearch
The approved drug 4-Aminopyridine can alleviate seizures and can support cognition in a subgroup of patients with developmental and epileptic #encephalopathy tied to the KCNA2 gene, according to a pilot trial. fcld.ly/9h42jhu @ScienceTM
A high-salt diet may help suppress tumors by modulating the gut microbiome, according to a new study in mice from @ScienceAdvances. fcld.ly/kxo04up
How microbiota improve immunotherapy: New research shows that members of the Enterococcus genus promote immunotherapy responses in mice through immunostimulatory muropeptides, which are structural units of bacterial cell walls. fcld.ly/yuzmm2w #SciencePerspective
Rapid warming in the Arctic is a likely driver of the recent extreme winter weather in the U.S., finds a new Science study, which establishes a physical link between anthropogenic #ClimateChange and the stratospheric polar vortex disruption. fcld.ly/bm824ks
New engineered anti-sperm antibodies show strong potency and stability and can trap mobile sperm with 99.9% efficacy in a sheep model, suggesting the antibodies could provide an effective, nonhormonal female contraception method. fcld.ly/44vsr8d
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