Nick Krontiris

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Resting heart rate, self-reported physical activity in middle age, and long-term risk of hip fracture. A NOREPOS cohort study of 367,386 men and women (open access) doi.org/10.1016/j.bone… #exercise #muscle #strength #lift #GetStrong #cardio #hiit
- The highest risk of hip fracture was found in men and women with a high resting heart rate, who also reported low levels physical activity in of their leisure time.
This one found a lower resting heart rate, a surrogate of physical fitness, and higher levels of self-reported physical activity in leisure time during middle-age to be associated with a lower long-term risk of hip fractures.
Haemostasis and fibrinolysis after regular high-intensity interval training in patients with coronary artery disease: a randomised controlled trial (open access) dx.doi.org/10.1136/openhr… #exercise #GymLife #GymTime #muscle #strength #lift #GetStrong #cardio #hiit
- 12 weeks of supervised high-intensity interval training did not affect markers of platelet aggregation, thrombin generation or fibrinolysis in patients with CAD.
The findings of this one does not support the hypothesis that the health-beneficial effect of regular exercise training are linked to changes in haemostasis or fibrinolysis in patients with stable coronary artery disease.
Maternal obesity alters offspring liver and skeletal muscle metabolism in early post-puberty despite maintaining a normal post-weaning dietary lifestyle (open access) doi.org/10.1096/fj.202… #nutrition #diet #Obesity #MetabolicSyndrome #Women #pregnancy
This one in baboons finds that maternal obesity during pregnancy may lead to early tissue metabolic impairment in the liver and muscle of the offspring, giving rise to the dysregulation of key metabolic pathways that are involved in carbohydrate and amino acid metabolism.
Metabolic & microvascular function assessed using NIRS W vascular occlusion in women From @Emily_Rogers @BanksNile @njenkinsphd "our data suggest that ageing is assoc W ⬇️skeletal muscle metabolic & microvascular hyperaemic responsiveness in women" doi.org/10.1113/EP0905…
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The joint associations of physical activity and TV viewing time with COVID-19 mortality: An analysis of UK Biobank doi.org/10.1080/026404… #MetabolicSyndrome #Obesity #exercise #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #GetStrong #cardio #hiit
- That is to say, highly active individuals with a high TV viewing time were still at higher risk of COVID-19 mortality compared to highly active individuals with a low TV viewing time, but this elevated risk was no longer statisticallly significant following adjustment for BMI.
- The individual and combined associations of a low physical activity level and a high TV viewing time with COVID-19 mortality were largely explained by higher levels of adiposity.
- The risk observed for the combination of a low physical activity level and a high TV viewing time was particularly pronounced and corresponded to a greater than two fold higher risk when compared to the highly active, low TV viewing time reference group.
- Across all physical activity levels, a high TV viewing time was associated with a greater risk of COVID-19 mortality.
This one found that a high TV viewing time may be a risk factor for COVID-19 mortality even amongst highly active individuals, if they are living with obesity.
So I guess I should stress that even though they do make some sense (drop sets = more stress => more need to deload in the longer term => it evens out in the macrocycle) it may be wise to interpret these results with caution.
"...After scrutinizing the full texts of these studies, we determined that 5 met inclusion criteria for at least one outcome measure"
Interestingly, "...initial search revealed 116 studies of potential relevance to this review. After removal of duplicates, we screened 52 records, of which 10 were considered for eligibility...
This systematic review and meta-analysis suggests that both drop set and traditional resistance training exercise are viable options for promoting muscular adaptations, as they have similar effects on muscular strength and hypertrophy.
Increased visceral fat area to skeletal muscle mass ratio (VSR) is positively associated with the risk of cardiometabolic diseases in a Chinese natural population: A cross-sectional study (open access) doi.org/10.1002/dmrr.3… #Obesity #muscle #exercise
This one found an increased visceral fat area to skeletal muscle mass ratio to be associated with the risk of cardiometabolic diseases, with the effect being stronger in women, in Chinese adults with a mean age of ~45 years.
Muscle researchers: today, 16-18 h Berlin/Munich time research seminar organised by @DrStefan2 with @martamurgia and Zudin Puthucheary on muscle wasting in ICU patients. #myotwitter @JCSM_cachexia @ICS_updates @I_C_N @WomenICM @CancerCachexia @SarcopeniaManag @dfg_public
Retweeted by Nick Krontiris
- An additive interaction between shift work and vitamin D deficiency in the development of metabolic syndrome was also observed.
- Shift workers were more likely to be vitamin D deficient than day workers, and vitamin D deficiency increased the risk of metabolic syndrome among shift workers.
Findings suggested a synergistic interaction between shift work and vitamin D deficiency in metabolic syndrome:
This one found found that vitamin D partially mediates the relationship between shift work and metabolic syndrome.
New Pub from Dr Willoughby's Lab! Honored to be a part of it! @TomCardaci "...we conclude that RE increases decorin within the ECM which is then able to bind to and subsequently decrease the amount of myostatin..." jssm.org/jssm-21-616.xm… via @j_s_s_m
Retweeted by Nick Krontiris
"これは、筋肉におけるビタミンDを介したミトコンドリア経路の証拠を発見したもので、ビタミンD欠乏が筋肉細胞におけるATP利用率の悪化、および脂肪量の増加と筋肉量の減少に関連した全身エネルギー消費の減少につながる可能性を示唆しています" twitter.com/nick_krontiris…
Retweeted by Nick Krontiris
Association between short sleep duration and intake of sugar and sugar-sweetened beverages: A systematic review and meta-analysis of observational studies (open access) doi.org/10.1016/j.sleh… #nutrition #diet #sleep
Grain of salt/me thinking out loud warning: Caffeine?
...while in adults, the analysis revealed a negative effect of sugar-sweetened beverage intake on sleep duration.
- The meta-analysis showed that short sleep duration (vs. sufficient sleep duration) in children was associated with higher intakes of sugar, soda, and energy drink intake...
- Most studies also found that sleep duration is likely to be negatively affected by sugar-sweetened beverage intake in both children and adults.
- Most of the studies found that sleep duration is likely to be negatively affected by total sugar intake in children, but not in adults.
- Among 34 observational studies, 22 were conducted among children, and 12 among adults.
This systematic review and meta-analysis suggests that sleep duration in children is likely to be negatively affected by total sugar intake, while in both children and adults, it is likely to be negatively affected by sugar-sweetened beverage intake.
How do cells regulate changes in protein expression levels upon external stimulation? Happy to share our new preprint addressing this question, by super-talented PhD student Benjamin Martin biorxiv.org/content/10.110… A brief 🧵
Retweeted by Nick Krontiris
Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis (open access) doi.org/10.1016/j.celr… #MetabolicSyndrome #Obesity #appetite
...which may in turn imply that the preventing hyperglycemia is important in order to harness the full benefit of GLP-1R agonists.
This study in mice suggests that insulin-induced hypoglycemia enhances GLP-1R agonists entry in hypothalamic and area, leading to enhanced whole-body fat oxidation, an effect blunted in obesity...
🚨 Being physically active may be associated with better#COVID199 outcomes 🏃‍♀️😷 11% lower risk of illness 36% lower risk of hospitalisation 34% lower risk of severe illnes#BJSMBloglog with excellent video summary 🎥 WATCH HEREbit.ly/3x75Ypawb9os
Retweeted by Nick Krontiris
“More gain, less pain: How resistance training affects immune system functioning in multiple sclerosis patients: A review (open access)” twitter.com/nick_krontiris…
Retweeted by Nick Krontiris
A DETAILED INVESTIGATION OF MULTIPLE RESTING CARDIOVASCULAR PARAMETERS IN RELATION TO PHYSICAL FITNESS (open access) doi.org/10.1111/cpf.12… #exercise #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #GetStrong #cardio #hiit
This one found smoking, arterial stiffness, lung function, fat mass, pulse pressure, and HDL-c to be associated with V'O2max, explaining 21% of its variation, in individuals aged 50 years living in Sweden.
More gain, less pain: How resistance training affects immune system functioning in multiple sclerosis patients: A review (open access) doi.org/10.1016/j.msar… #exercise #Workout #TrainHard #GymLife #GymTime #muscle #strength #lift #GetStrong
This review suggests that resistance training can be beneficial in patients with multiple sclerosis in terms of ameliorating fatigue, increasing functionality and mobility, and affecting key players of the immune system, ultimately contributing to their overall well-being.
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