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Patients with renal-cell carcinoma who undergo nephrectomy have few options for adjuvant therapy to reduce the recurrence risk.
Nicholas Bagley, J.D., discusses the Supreme Court’s decision in California v. Texas.
Environmental Racism and Climate Change
Bringing clinicians into payment reform models is vital. Strengthening current participation incentives could set up long-term benefits.
Image Challenge Follow-up: Computed tomography of the abdomen revealed multiple gastric polyps and gastrogastric intussusception in a patient with Peutz–Jeghers.
Broadly Neutralizing Antibodies against All Coronaviruses #COVID19 #IDTwitter
Breakthrough #SARSCoV2 Infections in Health Care Workers #IDTwitter
In a 1,000-patient trial, pembrolizumab injections led to improved disease-free survival at 2 years.
The editors look at new studies shedding light on diverse aspects of immunity: breakthrough infections, antiserum as therapy, and the potential breadth of the immune response. #COVID19 #IDTwitter
Myocarditis after Covid-19 mRNA Vaccination
Environmental racism includes the use of racist practices in determining which communities receive health-protective, and which health-harming, infrastructure.
Four out of 1,137 vaccinated health care workers had mild Covid-19 symptoms 62 days after a second vaccine dose. All four were infected with the B.1.1.7 strain.
Two patients are diagnosed with myocarditis 2 weeks after receiving #COVID19 mRNA vaccinations. One received BNT162b2; the other received mRNA-1273. #IDTwitter
Immunity against all beta-coronaviruses may be achievable. New data are reviewed from SARS-CoV-1 survivors immunized with a #SARSCoV2 mRNA vaccine. #IDTwitter
Convalescent plasma did not prevent disease progression in patients seen in EDs within 7 days after the onset #COVID19 symptoms. #IDTwitter
Our September issue explores difficult care for complex patients, Covid-19 #AdvanceCarePlanning, monoclonal antibody therapy distribution, transfers between collaborating hospitals, cataract surgery comparisons in three countries, and #DementiaCare:…
Retweeted by NEJM
In this editorial, Quarraisha Abdool Karim, Ph.D., reviews Landovitz et al.’s report on the results of a noninferiority trial for HIV prevention.
Daily oral tenofovir disoproxil fumarate–emtricitabine is one option for preexposure HIV prophylaxis.
Visual Abstract - Abelacimab for Prevention of Venous Thromboembolism
With the unfolding roles of glycoRNAs in autoimmunity and cancer, the discovery of a class of molecules opens a new frontier in glycobiology.
The ability to block specific cytokine pathways has revealed pathophysiological differences among autoimmune diseases.
In its first year, Medicare's Bundled Payments for Care Improvement–Advanced subsidized payments at participating hospitals.
Post-vaccination SARS-CoV-2 infections were generally mild or asymptomatic in healthcare workers who had received the Pfizer BNT162b2 #vaccine: #COVID19
Retweeted by NEJM
A patient was referred to the hematology clinic for anemia evaluation. A bone marrow biopsy and copper lab studies were performed.
NEJM Image Challenge: A patient with the Peutz–Jeghers syndrome presented with vomiting. A tender mass was found in the upper abdomen. What is the diagnosis?
Steven Phillips, M.D., M.P.H., discusses questions and concerns about ongoing symptoms related to Covid-19 in many patients.
With the delta #COVID19 variant spreading globally, the effectiveness of the BNT162b2 and ChAdOx1 nCoV-19 vaccines has been unclear. #IDTwitter
A Monoclonal Antibody for Malaria Prevention
The application process for 2022-2023 @NEJM Editorial Fellowship will close Sunday, August 15. Submit your application now.
Partake in this interactive feature about estimating the risk of coronary disease.
Antiviral medication has become a key tool in HIV infection prevention. In this trial, cabotegravir was found to prevent incident HIV.
NEJM Image Challenge Follow-up: Six human botfly larvae were extracted from patient with pruritic, draining nodules.
Third Time’s a Charm—Covid-19 Vaccine Hope for Solid Organ Transplant Recipients #Covid19vaccine #IDTwitter
A patient with hypertension was admitted with fever, sore throat, confusion, and a “lump” in the neck. A diagnostic test was performed.
For one physician, a year of telephone care during #COVID19 cultivated a capacity to connect with patients solely through sound.
The editors look at new studies of vaccine booster shots in immunocompromised persons, as well as monoclonal antibodies to prevent
A Randomized Trial of Third Dose mRNA-1273 Vaccine in Transplant Recipients #COVID19 #IDTwitter
In this report, an engineered monoclonal antibody showed protection against malaria infection in a controlled human infection model.
In this editorial, Winfred W. Williams, M.D., and Julie R. Ingelfinger, M.D., discuss the future for organ transplant recipients in the #COVID19 pandemic.
The authors conclude that a third-dose booster of mRNA-1273 vaccine should be considered for transplant recipients.
The phenotypes of VITT were defined in 220 patients presenting a 14-day median after the first ChAdOx1 nCoV-19 dose. Mortality was 22%. #COVID19 #IDTwitter
The mRNA-1273 vaccine was effective in preventing #COVID19 in 12-to-17-year-olds. Immune response was similar to young adults.
#COVID19 is an independent risk factor for acute myocardial infarction and ischemic stroke, suggest population-based studies in Sweden. @hmkyale
Retweeted by NEJM
Quick Take: Glucose Control in Type 2 Diabetes
Treatment of neovascular AMD with anti–vascular endothelial growth factor pharmacotherapy can reduce risk of AMD progression.
Visual Abstract: Milrinone vs. Dobutamine in Cardiogenic Shock
A patient presented with 10 years of severe diffuse abdominal pain events, occurring every month or two, lasting several days.
A patient with refractory SLE with active lupus nephritis had a complete response to CD19-specific chimeric antigen receptor T cells.
In a trial conducted in Norway, decompression surgery alone was noninferior to decompression with instrumented fusion.
In this editorial, Bloom et al. introduce a new editorial series on the fundamentals of public health.
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