Nature Cell Biology

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NEW ONLINE: @LabFuchs and colleagues report that THY1 regulates cell-matrix and cell-cell interactions to orchestrate YAP activity during skin homeostasis and regeneration. PDF: rdcu.be/cRgJl nature.com/articles/s4155…
Read also the News & Views article by Jeremy F. Reiter and Dhivya Kumar on the above study: "A kinesin mimics DNA" PDF: rdcu.be/cRcoW nature.com/articles/s4155…
NEW ONLINE: @DanweiHuangfu, Christina Leslie & colleagues show that HHEX safeguards pancreatic lineage over alternative fates by guiding FOXA1, FOXA2 and GATA4 to activate pancreatic genes and restricting plasticity. PDF: rdcu.be/cRcmB nature.com/articles/s4155…
See also the News & Views article by Alex S. Holehouse and Ryan J. Emenecker on the above study: "Intrinsically disordered CO2 sensors" PDF: rdcu.be/cRbCZ nature.com/articles/s4155…
Online now! In this Turning Point, Sarah-Maria Fendt discusses how research is a process. Enjoy the read☕️ Read for free: rdcu.be/cQJLy nature.com/articles/s4155…
Experts @CherylArrowsmi1 from @thesgconline, @target2035, @uoftmedicine and Paul Workman from @ICR_London, @Chemical_probes talked to Nature Communications about the use of #ChemicalProbes to study protein function in cells and organisms [go.nature.com/3R8aR9V ].
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NEW ONLINE: @lab_szabo and team show that ZBTB43 alters Z-DNA structures to prevent deleterious double-strand breaks and promote DNA methylation at purine-pyrimidine repeats in the mouse germ line PDF: rdcu.be/cQ6Ar nature.com/articles/s4155…
Read also the News & Views article written on the study by Craig P. Hunter and Nicole M. Bush: "Don’t put all your epigenetic eggs in one basket" PDF: rdcu.be/cQNmv nature.com/articles/s4155…
NEW ONLINE: Dapl1 modulates NFATc2 activation, thereby regulating CD8+ T cell exhaustion and responses in chronic infection and cancer. PDF: rdcu.be/cQNlZ nature.com/articles/s4155…
Online now! Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo dlvr.it/SSxJs3
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NEW ONLINE: TORC1 inhibition in yeast leads to chaperone ADC17 mRNA localization to cortical actin patches, where its translation is enhanced upon stress. PDF: rdcu.be/cQp0y nature.com/articles/s4155…
NEW ONLINE: ZNFX-1 maintains a pool of small RNA-targeted transcripts in perinuclear condensates of the C. elegans germline, which serve as templates for small RNA amplification in the next generation. PDF: rdcu.be/cQn9H nature.com/articles/s4155…
NEW ONLINE: @parentclab and team identify a pathway for exosome generation in immune cells that originates at the nuclear envelope and is facilitated by nSMase1-mediated generation of ceramide. PDF: rdcu.be/cQlgJ nature.com/articles/s4155…
NEW ONLINE: Hedgehog pathway kinesin KIF7 binds to GLI via electrostatic coiled-coil interactions and synergy between KIF7 and GLI underlies the recruitment to microtubules and the cilium tip. PDF: rdcu.be/cQgFV nature.com/articles/s4155…
NEW ONLINE: @Nina_CabezasW and team identify the hyaluronic acid-GPRC5C signaling axis as an essential component controlling human and murine haematopoietic stem cell dormancy. PDF: rdcu.be/cQe6m nature.com/articles/s4155…
NEW ONLINE: Group of PP2C phosphatases is responsible for direct sensing of CO2 in the environment via phase separation of an intrinsically disordered region. PDF: rdcu.be/cQbO8 nature.com/articles/s4155…
NEW ONLINE: An optimized Ribo-seq protocol applicable for low-input samples by Wei Xie, Lei Li and colleagues reveals the translation landscape during oocyte-to-embryo transition and in pre-implantation embryos. PDF: rdcu.be/cP6Qr nature.com/articles/s4155…
Read also News & Views article on the study above by Anne Brunet and Jason Wayne Miklas: "Long life depends on open communication" rdcu.be/cP6QV nature.com/articles/s4155…
Read also the News & Views article by Sergi Aranda, Livia Condemi and Luciano Di Croce. "PRC2 shields the potency of human stem cells" rdcu.be/cP55I nature.com/articles/s4155…
NEW ONLINE: H3K27me3 deposited by polycomb repressive complex 2 represents an epigenetic barrier that restricts naive human pluripotent cell differentiation into alternative lineages. PDF: rdcu.be/cP57A nature.com/articles/s4155…
Read also the News & Views article by Sergi Aranda, Livia Condemi and Luciano Di Croce. "PRC2 shields the potency of human stem cells" rdcu.be/cP55I nature.com/articles/s4155…
Read also the News & Views article written on the study by @GiorgiaQuadrato Marcella Birtele and @AlexanderAtami1: "Not all cortical organoids are created equal" rdcu.be/cP53Z nature.com/articles/s4155…
NEW ONLINE: A method to overcome limited cortical cellular diversity in human organoids enables mirroring fundamental features of cortical development. PDF: rdcu.be/cP53l nature.com/articles/s4155…
We celebrate Pride Month by proudly presenting to you our first World View: Dr. Chan provides his perspective on the meaning of Pride, ongoing challenges and progress towards LGBTQIA+ acceptance. PDF: rdcu.be/cP08F nature.com/articles/s4155…
📢Our June issue is live! On the cover: Fat-to neuron#lipidsignalingg! Read a Review on#RNAA imaging, research on#pluripotentcellss,#macropinosomee,#mechanicalforcee,#longevityy,#stressresponsee,#riboseqq,#organoidd,#lipidfluxx methods & more! nature.com/ncb/volumes/24…uIN
Currently at #ISSCR2022 ? Come “meet the editors” today, Friday 17 at 15.00-16.30 on Level 2 (tables)! Talk to: @vgebala from @Nature Kathryn Ascheim from @NatureBiotech @s_lefkopoulos from @NatureCellBio And @madhuramukho from @naturemethods We ‘re looking forward!
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NEW ONLINE: @vincentpasque @RuggGunnLab @hendrik_marks @MaartenDhaenens and colleagues report that PRC2 activity acts as a chromatin barrier restricting the differentiation of naive cells towards the trophoblast lineage. PDF: rdcu.be/cPLhp nature.com/articles/s4155…
Latest Review by Phuong Le, Noorsher Ahmed & Gene Yeo @yeo_lab discusses technologies for imaging RNA in fixed and live cells! Download pdf: rdcu.be/cPJjj nature.com/articles/s4155…
Let it begin! If you ‘re around, don’t hesitate to come and say hi or drop me a message to talk about your work for @NatureCellBio !!! #isscr2022
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Our Nature Cell Biology review by postdoc Phuong Le and grad student Noorsher Ahmed on how researchers explore RNA biology through imaging with high spatial resolution is now online rdcu.be/cPyvt
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NEW ONLINE: Lysosomal lipolysis in peripheral adipose depots produces polyunsaturated fatty acids that together with the lipid chaperone LBP-3 induce a neuropeptide-mediated cascade in neuros to extend lifaspan. PDF: rdcu.be/cPFYk nature.com/articles/s4155…
Stem cell-based embryo models can be used to study early human embryogenesis. @metricausa checks in with scientists on ethics and gauging how true the models are to the 'real thing.' nature.com/articles/s4159…
Retweeted by Nature Cell Biology
NEW ONLINE: Hexokinase 2 localizes in the nucleus of leukaemic and normal hematopoietic cells and maintains stemness by modulating chromatin accessibility independently of its kinase activity. PDF: rdcu.be/cPzgg nature.com/articles/s4155…
NEW ONLINE: @KornmannLab @ATJohnPeter and colleagues develop METALIC, an approach to track interorganelle lipid flux in live cells. PDF: rdcu.be/cPxpQ nature.com/articles/s4155…
NEW: Mechanical force application to the nucleus regulates nucleocytoplasmic transport by @AndreuIon, @i_GraneroMoya, @PCusachs & colleagues. 👉 link:nature.com/articles/s4155…c Image credit: Image courtesy of Institute for Bioengineering of Catalonia, designed by Eftichia TsoukalaH
Getting ready for the #ISSCR2022? Browse this new collection on #stemcells across Nature journals featuring articles on embryonic development, stem cell-based tissue engineering and translational research. nature.com/collections/if…
NEW ONLINE: Tetraspanin proteins assemble a rigid ring structure around damaged plasma membrane to prevent wound expansion, thereby facilitating membrane repair. PDF: rdcu.be/cPt1b nature.com/articles/s4155…
NEW ONLINE: ATF4 regulates collagen biosynthesis in perivascular cancer-associated fibroblasts to support angiogenesis and progression in melanoma and pancreatic cancer. PDF: rdcu.be/cPrvQ nature.com/articles/s4155…
NEW ONLINE: miR-122 encapsulated in breast cancer-derived extracellular vesicles targets PKM and leads to dysregulated glucose homeostasis and enhanced tumor growth. PDF: rdcu.be/cPoTW nature.com/articles/s4155…
NEW ONLINE: 3' UTR splicing is pervasively enhanced across different cancer types and drives tumourigenesis. PDF: rdcu.be/cPnHA nature.com/articles/s4155…
NEW ONLINE: A study by @josh_brickman , Ala Trusina and colleagues deconstructs endodermal cell fate trajectories and identifies the central intermediate in the extra-embryonic to embryonic endoderm transition. PDF: rdcu.be/cPj1k nature.com/articles/s4155…
NEW ONLINE: m6A mapping method optimized for ultra-low input material to characterize the m6A transcriptome-wide landscape in oocytes and early embryos. PDF: rdcu.be/cPiOt nature.com/articles/s4155…
NEW ONLINE: The proton-activated Cl- channel ASOR/TMEM206 required for shrinkage of macropinosomes and downstream sorting events. PDF: rdcu.be/cPely nature.com/articles/s4155…
📢 Check out the papers in our latest issue! Enjoy this Perspective on#lncRNAA and exciting research about#PhaseSeparationn,#HeartRegenerationn,#HSCC,#MitoticEntryy,#Pluripotencyy,#MitochondrialDNAA and many more! Click here👇☕nature.com/ncb/volumes/24…FTZ
Our stem cells and development editor @s_lefkopoulos is attending in person the ISSCR meeting this June! Feel free to reach out to him online or in person. twitter.com/s_lefkopoulos/…
Register for free and join us for exciting virtual talks & posters in November: conferences.nature.com/Metabolism22 #NatConfMetabolism twitter.com/NatureConf/sta…
In a move towards better reporting on sex and gender in research studies, researchers who submit papers to some Nature Portfolio journals will be prompted to state whether and how sex and gender were considered in their study design, or to clarify why not: go.nature.com/3NiVqcc
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Our senior editor @drDJVDavid is attending #EESMechanobiology in person! Feel free to reach out to him in person and online. twitter.com/drDJVDavid/sta…
Check out the News&Views by Louk Theodoor Timmer & Eva van Rooij: Defining the pathways of heart regeneration rdcu.be/cNBu6
NEW study led by Kupatt, Fritsche-Danielson, Moretti, Chien & Laugwitz: Human cardiac progenitors target loss of myocardium and fibrotic scarring to promote heart regeneration. rdcu.be/cNBuX nature.com/articles/s4155…
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