JAMA

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#Viewpoint: recent legal directives by @HHSGov & FDA that could increase health care entities’ liability for possible discriminatory biases of clinical algorithms & the need for additional legal clarity to avoid adverse effects on algorithm dev & use. ja.ma/3HzkLyI
9h
The @cms proposed a rule to standardize electronic signatures and health care attachment transactions, such as medical charts and x-rays. If finalized, the rule would also standardize notes for referrals and office and #telehealth visits. ja.ma/3H7XDWi #MedicalNews
11h
Medical News in Brief: Wildfire Exposure Linked to Changes in Cognition and Brain Activity ja.ma/3H3VQBT
20h
Rabies is a very rare but deadly disease caused by the rabies virus. This JAMA Patient Page describes #rabies and its symptoms, diagnosis, and prevention measures. ja.ma/3ZXc9Jf
This JAMA Insights in the Women's Health series reviews the risk factors for and symptoms of lactational mastitis and provides a potential treatment algorithm. ja.ma/3kOmBT9
Among cohorts in 5 US states, there was a significantly increased risk of household transmission of influenza A(H3N2) in 2021-2022 compared with prepandemic seasons. ja.ma/3j82KxT
#Viewpoint: a proposed @HHSGov rule to address discrimination in clinical algorithms and the need for additional considerations to ensure the burden of liability for biased algorithms is not disproportionately placed on health care professionals. ja.ma/3ZTFAMt
The Administration on Aging released updated demographics for the US population aged 65 years or older. Data were sourced from @BLS_gov, @NCHStats, and @uscensusbureau. ja.ma/3kDqNp0 #MedicalNews
Medical News in Brief: Changes in p53 Gene May Influence Cardiovascular Disease Risk ja.ma/3H3VQ4R
Hospitals in Ethiopia have resorted to sterilizing and reusing surgical gloves, using expired drugs, and ventilating critically ill patients with manual bags for hours at a time. Larkin reports on the collapse of health care systems in the war-torn country ja.ma/3j4R8vC
In this retrospective study of predictive accuracy, existing stroke-specific risk prediction models and novel machine learning techniques did not significantly improve discriminative accuracy for new-onset stroke compared with the pooled cohort equations. ja.ma/3j6zDef
A large cohort study found a possible association between postural orthostatic tachycardia syndrome (#POTS) and COVID-19 vaccination. But the odds of developing POTS were 5 times greater after SARS-CoV-2 infection than after vaccination, @RitaRubin reports ja.ma/3DegsWM
More reason to take the stairs: a new study suggests that short bursts of vigorous activity in everyday life could slash the risk of death from all causes, cancer, and cardiovascular disease. ja.ma/3RagaGo #MedicalNews
Several agencies under @HHSGov aren’t adequately shielded against political interference, according to a report by @gao. ja.ma/3R2szfg #MedicalNews
Medical News in Brief: Patients with mild COVID-19 at risk for some long COVID symptoms ja.ma/3Hc500n
Listen to a summary of the January 24 issue of JAMA by Editor in Chief @KBibbinsDomingo. ja.ma/3J8mNad
A growing number of U.S. hospitals and medical practices have begun charging fees for doctors’ responses to patient queries. The fees may be discouraging at least a small percentage of patients from getting medical advice via email, a new study says. nyti.ms/4000kSI
Retweeted by JAMA
Medical News in Brief: Sickle cell disease gene therapy trial paused ja.ma/3WAz36f
In 2018, health system physicians and hospitals delivered a large portion of medical services. Performance on clinical quality and patient experience measures was marginally better in systems but spending and prices were substantially higher. ja.ma/3J8mNqJ
Among outpatients with mild to moderate #COVID19, treatment with 50 mg of fluvoxamine twice daily for 10 days, compared with placebo, did not improve time to sustained recovery. ja.ma/3kBa59E
#Viewpoint reviews the anatomical body procurement used in Nazi Germany, notes the continued use of those images, and calls for disclosure of the biographical history of the people whose bodies and tissues are now studied. ja.ma/3GMWH9N
Medical News in Brief: Letters to clinicians may promote better-informed opioid prescribing ja.ma/3ZM9Qsh
The FDA recently cautioned that noninvasive body contouring technologies could cause pain, redness, and swelling, among other problems. ja.ma/3XzlFAj #MedicalNews
Medical News in Brief: AAP recommends immediate, intensive treatment for child obesity ja.ma/3Hz3eGZ
The labeling for capecitabine, a 25-year-old drug marketed as Xeloda, recently got a refresh as part of a pilot program to update labeling for some older oncology medications. ja.ma/3wa76Yc #MedicalNews
Atopic dermatitis (eczema) is a skin condition that can cause redness, swelling, scaling, oozing/weeping, and dryness. This JAMA Patient Page describes atopic dermatitis and its symptoms and treatment options. ja.ma/3kgELwB
JAMA Guide to Statistics and Methods article examines conditional power, calculated while a trial is ongoing and based on both the currently observed data and an assumed treatment effect for future patients. ja.ma/3D7ZAks
#Viewpoint examines the first 50 years of the US End-Stage Renal Disease (ESRD) program, which extends Medicare benefits to people with kidney failure, including technological updates and continuing challenges to update cost and quality. ja.ma/3Xp89iT
The FDA recently approved the first gene therapy for treating high-risk bladder cancer that doesn’t respond to immunotherapy with bacillus Calmette- Guérin, commonly used to treat adults with non-muscle-invasive bladder cancer. ja.ma/3Heu4DL #MedicalNews
Medical News in Brief: NIH pilots telehealth program for COVID-19 ja.ma/3WgsuFL
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial, just presented at #SCCM2023, free to read online ja.ma/3iCofqu
Just presented at #SCCM2023: PARIS-2 trial on Effect of Early High-Flow Nasal Oxygen vs Standard Oxygen Therapy on Length of Hospital Stay in Hospitalized Children With Acute Hypoxemic Respiratory Failure. Free to read online ja.ma/3waKRRY
In 30 minutes at 1:45 PM PST at #SCCM2023, recent studies on acute hypoxemic respiratory failure and #COVID19 presented in the Late-Breaking Studies That Will Change Your Practice plenary session. Esplanade Ballroom.
Medical News in Brief: Child asthma tied to specific urban air pollutants ja.ma/3WjMzeA
Medical News in Brief: Gene edited tumor cells kill and prevent cancer in mice ja.ma/3GRugHP
#Viewpoint discusses the failure of the @CMSGov’s SEP-1 sepsis outcome improvement initiative to improve patients’ #sepsis outcomes and suggests changing the focus of sepsis quality metrics from processes to outcomes. ja.ma/3WpPFxA
A 62-year-old woman with a large abdominal mass. Take the Clinical Challenge. What would you do next? ja.ma/3XzQ6qa
Attending #SCCM2023? Catch the Late-Breaking Studies That Will Change Your Practice plenary session to hear recent research on acute hypoxemic respiratory failure and #COVID19. Saturday, January 21, 1:45 PM PST, Esplanade Ballroom.
Matched-cohort study uses data from the French National Health Insurance database to assess whether a 19.5-mg levonorgestrel intrauterine system, vs a 52-mg system, is associated with increased use of antidepressant, hypnotic, and anxiolytic medications. ja.ma/3XA2xC5
Viewpoint: @US_FDA leaders propose the creation of a comprehensive “care package” framework of resources to help maximize cessation of tobacco use, including components focused on strategies at the individual, health system, and population levels. ja.ma/3WmUojA
More young people around the world are being diagnosed with type 2 #diabetes. A survey of 204 countries found that high body mass index was the main contributing factor across all regions, but air pollution also played a role. ja.ma/3kgEKZz #T2D #MedicalNews
Medical News in Brief: Substance use, mental health challenges widespread in 2021 ja.ma/3GS8pzT
#Viewpoint reviews the mechanics of California’s #insulin initiative and the challenges it faces and suggests some broader implications if the effort proves successful. ja.ma/3iODM6u
In biobank populations, the presence of a supernumerary sex chromosome aneuploidy was associated with a small but statistically significant increased risk of VTE, but further research is needed to understand the clinical implications of this association. ja.ma/3iKBIMR
This JAMA Insights Clinical Update examines treatment recommendations and therapy options among adults with latent tuberculosis infection. ja.ma/3XEvnBs
Listen to a discussion about surgical site infection prevention. ja.ma/3w7B1QQ
Data from 87 countries show that bacteria that frequently cause life-threatening blood infections became more resistant to antimicrobial treatment between 2017 and 2020, according to a recent @WHO report. ja.ma/3iQW5rH #MedicalNews
Medical News in Brief: Lecanemab gains FDA approval for early Alzheimer disease ja.ma/3HewaDK
Review summarizes current evidence-based interventions for the prevention of surgical site infection that are applicable to the majority of operations. ja.ma/3waZSmS
A clinical trial in Australia tested a minimally invasive brain-computer interface implant that may allow people with #paralysis to control computers with their thoughts. Melissa Suran and @jenabbasi report on the study in @JAMANeuro. ja.ma/3HcNCbS #MedicalNews
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